PMP22 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Human cerebrum tissue，A172 cell，Mouse lung tissue，293T cell，231 cell，Mouse liver tissue，Mouse brain tissue lysates IHC: 20-100 Positive control: Human colorectal cancer Predicted cell location: Cell membrane
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human PMP22
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	18 kDa
Gene Name	peripheral myelin protein 22
Database Link	Entrez Gene 5376 Human UniProt ID Q01453
Background	This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.
Synonyms	CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; MGC20769; PMP-22; Sp110
Reference Data

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