Gemin 4 (GEMIN4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 30-150 Positive control: Human liver cancer Predicted cell location: Cytoplasm or Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human GEMIN4
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Gene Name	gem nuclear organelle associated protein 4
Database Link	Entrez Gene 50628 Human UniProt ID P57678
Background	The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Synonyms	DKFZp434B131; DKFZp434D174; Gemin-4; HC56; HCAP1; HHRF-1; p97
Reference Data

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