ASB8 Rabbit Polyclonal Antibody
CAT#: TA368984S
ASB8 rabbit polyclonal antibody
Size: 100 ul
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Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 25-100 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human ASB8 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Gene Name | ankyrin repeat and SOCS box containing 8 |
Database Link | |
Background | ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas. |
Synonyms | ASB-8; FLJ21255; MGC5540; PP14212 |
Reference Data |
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