UBAC2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: Mouse kidney tissue and Mouse brain tissue lysates
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human UBAC2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	39 kDa
Gene Name	UBA domain containing 2
Database Link	Entrez Gene 337867 Human UniProt ID Q8NBM4
Background	UBAC2 (ubiquitin-associated domain-containing protein 2), also known as PHGDHL1 (phosphoglycerate dehydrogenase-like protein 1), is a 344 amino acid multi-pass membrane protein that contains one UBA domain and is expressed as multiple alternatively spliced isoforms. The gene encoding UBAC2 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Synonyms	FLJ26351; FLJ30001; FLJ30548; FLJ42413; MGC90487; PHGDHL1; RP11-178C10.1
Reference Data

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