DDX59 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: A549 and 293T cell lysates IHC: 30-150 Positive control: Human tonsil Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human DDX59
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	69 kDa
Gene Name	DEAD-box helicase 59
Database Link	Entrez Gene 83479 Human UniProt ID Q5T1V6
Background	DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX59 (DEAD box protein 59), also known as ZNHIT5 (zinc finger HIT domaincontaining protein 5), is a 619 amino acid member of the DEAD box helicase protein family. Like many DEAD box helicase family members, DDX59 contains a Q motif, which controls ATP binding and hydrolysis. Expressed as two isoforms produced by alternative splicing, DDX59 contains one helicase C-terminal domain and one HIT-type zinc finger.
Synonyms	DKFZP564B1023; ZNHIT5
Reference Data

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