C17orf71 (SMG8) Rabbit Polyclonal Antibody
CAT#: TA371170
SMG8 rabbit polyclonal antibody
Size: 25 ul
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CNY 1,999.00
CNY 3,280.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 200-1000 WB positive control: TM4 cell lysate |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human SMG8 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Predicted Protein Size | 110 kDa |
Gene Name | SMG8, nonsense mediated mRNA decay factor |
Database Link | |
Background | Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity. |
Synonyms | 1200011M11Rik; RP23-352L3.2 |
Reference Data |
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