Complement C3 (C3) Rabbit Polyclonal Antibody
CAT#: TA372151S
C3/C3b rabbit polyclonal antibody
Size: 100 ul
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Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 20-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm and Cell membrane |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human C3/C3b |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Gene Name | complement component 3 |
Database Link | |
Background | Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. |
Synonyms | AHUS5; ARMD9; ASP; CPAMD1 |
Reference Data |
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