PNPO Rabbit Polyclonal Antibody
CAT#: TA372342S
PNPO rabbit polyclonal antibody
Size: 100 ul
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 500-2000 WB positive control: Human fetal brain tissue,PC-3,Hela and 293T cell lysates IHC: 20-100 Positive control: Human brain Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human PNPO |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Predicted Protein Size | 30 kDa |
Gene Name | pyridoxamine 5'-phosphate oxidase |
Database Link | |
Background | The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. |
Synonyms | FLJ10535; PDXPO |
Reference Data |
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