beta Actin (ACTB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB:1:5000~1:20000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Conjugation	Unconjugated
Predicted Protein Size	42 kDa
Gene Name	actin, beta
Database Link	Entrez Gene 60 Human UniProt ID P60709
Background	All eukaryotic cells express actin, which often constitutes asmuch as 50% of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of actin are present in mammalian tissues and fall into three classes. -actin expression is limited to various types of muscle, whereas – and -actin are the principle constituents of filaments in other tissues.Members of the small GTPase family regulate the organization of the actin cytoskeleton. Rho controls the assembly of ctin stress fibers and focal adhesion, Rac regulates ctin filament accumulation at the plasma membrane and Cdc42 stimulates formation of filopodia.
Synonyms	Beta-actin; PS1TP5BP1
Note	β-actin (I102) polyclonal antibody detects endogenous levels of β-actin protein.
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.