AKT2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:500 - 1:2000 IHC,1:50 - 1:100 ICC,1:50 - 1:200 IF,1:50 - 1:100 IP,1:20 - 1:50 ChIP,1:20 - 1:100
Reactivity	Human, Mouse
Modifications	Unmodified
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human AKT2
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	51kDa/55kDa
Gene Name	AKT serine/threonine kinase 2
Database Link	Entrez Gene 208 Human UniProt ID P31751
Background	This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
Synonyms	PKBB; PKBBETA; PRKBB; RAC-BETA; RAC-PK-beta
Reference Data

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