CDK1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, IHC, IP, WB
Recommend Dilution	WB,1:500 - 1:1000 IHC,1:50 - 1:200 IF,1:50 - 1:100 IP,1:50 - 1:100
Reactivity	Human, Mouse, Rat
Modifications	Phospho Y15
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic phosphorylated peptide around Y15 of human CDK1 (NP_001777.1).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	27kDa/34kDa
Gene Name	cyclin-dependent kinase 1
Database Link	Entrez Gene 983 Human UniProt ID P06493
Background	The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms	Cdc2; Cdc2a; p34
Reference Data

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