JAK3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, WB
Recommend Dilution	WB,1:500 - 1:2000 IF,1:50 - 1:100
Reactivity	Human
Modifications	Unmodified
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 750-850 of human JAK3 (NP_000206.2).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	68kDa/121kDa/125kDa
Gene Name	Janus kinase 3
Database Link	Entrez Gene 3718 Human UniProt ID P52333
Background	The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Synonyms	JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK
Reference Data

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