c-Myc (MYC) Rabbit Polyclonal Antibody

CAT#: TA378818

Phospho-c-Myc-T58 Rabbit polyclonal Antibody



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CNY 2,900.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB,1:500 - 1:2000
IHC,1:50 - 1:200
Reactivity Human, Mouse, Rat
Modifications Phospho T58
Host Rabbit
Clonality Polyclonal
Immunogen A phospho specific peptide corresponding to residues surrounding T58 of human MYC
Formulation PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size 48kDa/50kDa
Gene Name v-myc avian myelocytomatosis viral oncogene homolog
Background The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Synonyms bHLHe39; c-Myc; MRTL
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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