Mineralocorticoid Receptor (NR3C2) Rabbit Polyclonal Antibody
CAT#: TA379299
Mineralocorticoid receptor (NR3C2) Rabbit polyclonal Antibody
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CNY 1,999.00
CNY 3,280.00
货期*
2周
规格
经常一起买 (1)
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Specifications
Product Data | |
Applications | ICC/IF, IHC, WB |
Recommend Dilution | WB,1:500 - 1:2000 IHC,1:50 - 1:200 IF,1:50 - 1:200 |
Reactivity | Human, Mouse, Rat |
Modifications | Unmodified |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 800 to the C-terminus of human Mineralocorticoid receptor (NR3C2) (NP_001159576.1). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 75kDa/94kDa/107kDa |
Gene Name | nuclear receptor subfamily 3 group C member 2 |
Database Link | |
Background | This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. |
Synonyms | FLJ41052; MCR; MGC133092; MLR; MR; NR3C2VIT |
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