RbAp48 (RBBP4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ChIP, WB
Recommend Dilution	WB,1:500 - 1:2000 IF,1:50 - 1:200 ChIP,1:20 - 1:50
Reactivity	Human
Modifications	Unmodified
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-425 of human RBBP4 (NP_005601.1).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	43kDa/46kDa/47kDa
Gene Name	RB binding protein 4, chromatin remodeling factor
Database Link	Entrez Gene 5928 Human UniProt ID Q09028
Background	This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms	NURF55; RBAP48; RBBP-4
Reference Data

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