S6K1 (RPS6KB1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB,1:500 - 1:2000 IHC,1:50 - 1:200
Reactivity	Human, Mouse, Rat
Modifications	Phospho T389
Host	Rabbit
Clonality	Polyclonal
Immunogen	A phospho synthetic peptide corresponding to residues surrounding T389 of human P70S6K1.
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	59kDa
Gene Name	ribosomal protein S6 kinase B1
Database Link	Entrez Gene 6198 Human UniProt ID P23443
Background	This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Synonyms	p70(S6K)-alpha; p70-alpha; p70-S6K; P70S6K; PS6K; S6K; S6K1; STK14A
Reference Data

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