S Protein Rabbit Polyclonal Antibody
CAT#: TA381938
SARS-CoV-2 Spike RBD Rabbit polyclonal Antibody
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CNY 2,700.00
货期*
2周
规格
经常一起买 (1)
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Specifications
Product Data | |
Applications | ELISA, ICC/IF, IP, WB |
Recommend Dilution | ELISA,1:50000-1:200000 WB,1:500 - 1:2000 IF,1:50 - 1:200 IP,1:50 - 1:200 |
Reactivity | SARS-CoV-2 |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of SARS-CoV-2 Spike RBD. |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Gene Name | S Protein |
Database Link | |
Background | The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike is essential for both host specificity and viral infectivity. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It''s been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate. |
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