TDP43 (TARDBP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	Dot, WB
Recommend Dilution	WB,1:500 - 1:2000
Reactivity	Human
Modifications	Phospho S409/S410
Host	Rabbit
Clonality	Polyclonal
Immunogen	A phospho synthetic peptide corresponding to residues surrounding S409/S410 of Human TDP-43/TARDB.
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	31kDa/44kDa
Gene Name	TAR DNA binding protein
Database Link	Entrez Gene 23435 Human UniProt ID Q13148
Background	HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Synonyms	ALS10; TDP-43
Reference Data

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