TDP43 (TARDBP) Rabbit Polyclonal Antibody
CAT#: TA382309
Phospho-TDP-43/TARDB-S409/S410 Rabbit polyclonal Antibody
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CNY 2,900.00
货期*
2周
规格
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Specifications
Product Data | |
Applications | Dot, WB |
Recommend Dilution | WB,1:500 - 1:2000 |
Reactivity | Human |
Modifications | Phospho S409/S410 |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A phospho synthetic peptide corresponding to residues surrounding S409/S410 of Human TDP-43/TARDB. |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 31kDa/44kDa |
Gene Name | TAR DNA binding protein |
Database Link | |
Background | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. |
Synonyms | ALS10; TDP-43 |
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