TMEM100 Rabbit Polyclonal Antibody
CAT#: TA382594
TMEM100 Rabbit polyclonal Antibody
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CNY 1,999.00
CNY 3,280.00
货期*
2周
规格
经常一起买 (1)
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB,1:500 - 1:2000 |
Reactivity | Human, Mouse |
Modifications | Unmodified |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TMEM100 (NP_001093110.1). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 14kDa |
Gene Name | transmembrane protein 100 |
Database Link | |
Background | Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex. |
Synonyms | FLJ10970; FLJ37856 |
Reference Data |
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