Tetraspanin 33 (TSPAN33) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:200 - 1:1000 IHC,1:50 - 1:200
Reactivity	Human, Mouse, Rat
Modifications	Unmodified
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human TSPAN33 (NP_848657.1).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	31kDa
Gene Name	tetraspanin 33
Database Link	Entrez Gene 340348 Human UniProt ID Q86UF1
Background	Plays an important role in normal erythropoiesis (By similarity. It has a role in the differentiation of erythroid progenitors (By similarity. Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity. Mediates docking of ADAM10 to zonula adherens by interacting with ADAM10 and, in a PDZD11-dependent manner, with the zonula adherens protein PLEKHA7.
Synonyms	hPen; MGC50844; PEN; penumbra; Tspan-33
Reference Data

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