AMPK alpha 1 (PRKAA1) Rabbit Polyclonal Antibody
CAT#: TA383644
Phospho-AMPK alpha 1/2 (Thr183/Thr172) Rabbit polyclonal Antibody
Size: 20 ul
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Specifications
Product Data | |
Applications | ELISA, IF, IHC, WB |
Recommend Dilution | IF: 1/50-200 WB: 1/500-1/2000 IHC: 1/100-1/300 ELISA: 1/40000 |
Reactivity | Human, Mouse, Rat, Monkey, Pig |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189 (Phosphorylated) |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
Concentration | lot specific |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Predicted Protein Size | Observed MW (kDa):63 |
Gene Name | protein kinase AMP-activated catalytic subunit alpha 1 |
Database Link | |
Background | Swiss-Prot Acc.Q13131/P54646.Protein kinase AMP-activated catalytic subunit alpha 1 encoded by PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Synonyms | AMPK; AMPK1; AMPKa1; MGC33776; MGC57364 |
Reference Data |
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