Annexin A2 (ANXA2) Rabbit Monoclonal Antibody [Clone ID: R09-5C1]

Specifications

Product Data
Clone Name	R09-5C1
Applications	IF, WB
Recommend Dilution	WB: 1/1000 ICC/IF: 1/50
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human Annexin A2
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 39 kDa; Observed MW: 38 kDa
Gene Name	annexin A2
Database Link	Entrez Gene 302 Human UniProt ID P07355
Background	Swiss-Prot Acc.P07355.Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640).
Synonyms	Annexin-2; ANX2; ANX2L4; CAL1H; Chromobindin-8; LIP2; LPC2; LPC2D; P36; PAP-IV
Reference Data

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