ASH2L Rabbit Monoclonal Antibody [Clone ID: R05-7E1]

Specifications

Product Data
Clone Name	R05-7E1
Applications	IF, IHC, WB
Recommend Dilution	WB: 1/2000-1/10000 IHC: 1/20 ICC/IF: 1/500
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human ASH2L
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 69 kDa; Observed MW: 80 kDa
Gene Name	ASH2 like histone lysine methyltransferase complex subunit
Database Link	Entrez Gene 9070 Human UniProt ID Q9UBL3
Background	Swiss-Prot Acc.Q9UBL3.Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
Synonyms	ASH2; ash2-like; ASH2L1; ASH2L2; Bre2
Reference Data

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