Caspase 10 (CASP10) Rabbit Monoclonal Antibody [Clone ID: R03-2J3]

Specifications

Product Data
Clone Name	R03-2J3
Applications	IHC, IP, WB
Recommend Dilution	WB: 1/2000 IHC: 1/20 IP: 1/20
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human Caspase-10
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 59 kDa; Observed MW: 59 kDa
Gene Name	caspase 10
Database Link	Entrez Gene 843 Human UniProt ID Q92851
Background	Swiss-Prot Acc.Q92851.Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.
Synonyms	ALPS2; CASP-10; FLICE2; MCH4
Reference Data

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