Caspase 3 (CASP3) Rabbit Monoclonal Antibody [Clone ID: R08-6F2]

CAT#: TA383875S

Caspase 3 Rabbit monoclonal Antibody

Size: 20 ul 100 ul



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CNY 800.00


货期*
2周

规格
    • 20 ul

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Specifications

Product Data
Clone Name R08-6F2
Applications IHC, IP, WB
Recommend Dilution WB: 1/1000
IHC: 1/50
IP: 1/20
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Immunogen Recombinant protein of human Caspase-3
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size Calculated MW: 32 kDa; Observed MW: 32 kDa
Gene Name caspase 3
Background Swiss-Prot Acc.P42574.Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Synonyms apopain; CASP-3; CPP-32; CPP32; CPP32B; procaspase3; SCA-1; Yama
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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