HP1 gamma (CBX3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, IP, WB
Recommend Dilution	WB: 1/500-1/2000 IHC: 1/50-1/200 IP: 1/50 FC: 1/100
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human HP1 gamma
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	24kDa
Gene Name	chromobox 3
Database Link	Entrez Gene 11335 Human UniProt ID Q13185
Background	Swiss-Prot Acc.Q13185.Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Synonyms	HECH; HP1-GAMMA; HP1Hs-gamma
Reference Data

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