DNAJB6 Rabbit Monoclonal Antibody [Clone ID: R01-8K2]
CAT#: TA384111
DNAJB6 Rabbit monoclonal Antibody
Size: 20 ul
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CNY 1,999.00
CNY 3,280.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | R01-8K2 |
Applications | IHC, WB |
Recommend Dilution | WB: 1/1000 IHC: 1/20 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal |
Immunogen | Recombinant protein of human DNAJB6 |
Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Predicted Protein Size | Calculated MW: 36 kDa; Observed MW: 36 kDa |
Gene Name | DnaJ heat shock protein family (Hsp40) member B6 |
Database Link | |
Background | Swiss-Prot Acc.O75190.Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity. |
Synonyms | DJ4; DKFZp566D0824; DnaJ; FLJ42837; HHDJ1; HSJ-2; HSJ2; MGC1152; MGC117297; MRJ; MSJ-1; MSJ1 |
Reference Data |
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