EIF4A1 Mouse Monoclonal Antibody [Clone ID: 6D7-10D5-7H7]

Specifications

Product Data
Clone Name	6D7-10D5-7H7
Applications	IF, IHC, WB
Recommend Dilution	WB: 1/1000-3000 ICC: 1/100-200 IHC: 1/50-300
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic Peptide of eIF4A1
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Observed MW (kDa):48
Gene Name	eukaryotic translation initiation factor 4A1
Database Link	Entrez Gene 1973 Human UniProt ID P60842
Background	Swiss-Prot Acc.P60842.ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Synonyms	DDX2A; EIF-4A; eIF-4A-I; EIF4A; eIF4A-I
Reference Data

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