EIF4EBP1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, IHC, IP, WB
Recommend Dilution	WB: 1/1000-1/2000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 IP: 1/50 FC: 1/50
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human eIF4EBP1
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	18kDa
Gene Name	eukaryotic translation initiation factor 4E binding protein 1
Database Link	Entrez Gene 1978 Human UniProt ID Q13541
Background	Swiss-Prot Acc.Q13541.Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity.
Synonyms	4E-BP1; 4EBP1; BP-1; MGC4316; PHAS-I
Reference Data

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