FKBP52 (FKBP4) Rabbit Monoclonal Antibody [Clone ID: R03-4A3]

Specifications

Product Data
Clone Name	R03-4A3
Applications	IF, WB
Recommend Dilution	WB: 1/1000-1/5000 ICC/IF: 1/20-1/50
Reactivity	Human, Mouse, Rat, Hamster
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human FKBP52
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 52 kDa; Observed MW: 52 kDa
Gene Name	FK506 binding protein 4
Database Link	Entrez Gene 2288 Human UniProt ID Q02790
Background	Swiss-Prot Acc.Q02790.Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.
Synonyms	FKBP52; FKBP59; HBI; Hsp56; p52; PPIase; rotamase
Reference Data

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