Histone H2A.X (H2AFX) Rabbit Monoclonal Antibody [Clone ID: R02-5E6]

CAT#: TA384365S

Histone H2A.X Rabbit monoclonal Antibody

Size: 20 ul 100 ul



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CNY 800.00


货期*
2周

规格
    • 20 ul

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经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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CNY 300.00
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Specifications

Product Data
Clone Name R02-5E6
Applications IF, IHC, IP, WB
Recommend Dilution WB: 1/1000-1/5000
IHC: 1/200
ICC/IF: 1/200
IP: 1/20
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Immunogen A synthetic peptide of human Histone H2A.X
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size Calculated MW: 15 kDa; Observed MW: 15 kDa
Gene Name H2A histone family member X
Background Swiss-Prot Acc.P16104.Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Synonyms H2A.X; H2A/X; H2AX
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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