Heme Oxygenase 1 (HMOX1) Rabbit Monoclonal Antibody [Clone ID: R02-6C1]

Specifications

Product Data
Clone Name	R02-6C1
Applications	IF, IHC, IP, WB
Recommend Dilution	WB: 1/1000 IHC: 1/50 ICC/IF: 1/50 IP: 1/20
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of mouse Heme Oxygenase 1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 33 kDa; Observed MW: 33 kDa
Gene Name	heme oxygenase 1
Database Link	Entrez Gene 3162 Human UniProt ID P09601
Background	Swiss-Prot Acc.P09601.Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
Synonyms	bK286B10; HO; HO-1; HO1; HSP32
Reference Data

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