c-Jun (JUN) Rabbit Monoclonal Antibody [Clone ID: R02-1G3]

Specifications

Product Data
Clone Name	R02-1G3
Applications	IF, IP, WB
Recommend Dilution	WB: 1/1000 ICC/IF: 1/50 IP: 1/20
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human c-Jun
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 36 kDa; Observed MW: 48,43 kDa
Gene Name	Jun proto-oncogene, AP-1 transcription factor subunit
Database Link	Entrez Gene 3725 Human UniProt ID P05412
Background	Swiss-Prot Acc.P05412.Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
Synonyms	AP-1; AP1; c-Jun; p39
Reference Data

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