Cytokeratin 18 (KRT18) Rabbit Monoclonal Antibody [Clone ID: R03-5E3]

Specifications

Product Data
Clone Name	R03-5E3
Applications	IF, IHC, WB
Recommend Dilution	WB: 1/2000 IHC: 1/50 ICC/IF: 1/50
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human Cytokeratin 18
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 48 kDa; Observed MW: 48 kDa
Gene Name	keratin 18
Database Link	Entrez Gene 3875 Human UniProt ID P05783
Background	Swiss-Prot Acc.P05783.Involved in the uptake of thrombin-antithrombin complexes by hepatic cells . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Synonyms	CK-18; CYK18; Cytokeratin-18; K18; Keratin-18
Reference Data

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