MIF Rabbit Monoclonal Antibody [Clone ID: R05-8H5]

Specifications

Product Data
Clone Name	R05-8H5
Applications	WB
Recommend Dilution	WB: 1/1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human MIF
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 13 kDa; Observed MW: 13 kDa
Gene Name	macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Database Link	Entrez Gene 4282 Human UniProt ID P14174
Background	Swiss-Prot Acc.P14174.Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Synonyms	GIF; GLIF; MMIF
Reference Data

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