MLKL Mouse Monoclonal Antibody [Clone ID: 5E3-6B4-7G9]

Specifications

Product Data
Clone Name	5E3-6B4-7G9
Applications	IHC
Recommend Dilution	IHC: 1/100-200
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide conjugated to KLH.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	54kDa
Gene Name	mixed lineage kinase domain-like
Database Link	Entrez Gene 197259 Human UniProt ID Q8NB16
Background	Swiss-Prot Acc.Q8NB16.Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Synonyms	FLJ34389
Reference Data

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