LIMS1 Mouse Monoclonal Antibody [Clone ID: 3C12-F7-A8]
CAT#: TA384985
PINCH (3C12) Mouse monoclonal Antibody
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CNY 1,999.00
CNY 3,280.00
货期*
2周
规格
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | 3C12-F7-A8 |
Applications | FC, IF, IP, WB |
Recommend Dilution | WB: 1/500-1/2000 ICC: 1/200-1/1000 FC: 1/200-1/400 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human PINCH expressed in E. Coli. |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3. |
Concentration | lot specific |
Purification | Ascitic Fluid |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Predicted Protein Size | 37kDa |
Gene Name | LIM zinc finger domain containing 1 |
Database Link | |
Background | Swiss-Prot Acc.P48059.The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. |
Synonyms | OTTHUMP00000161608; PINCH; PINCH-1; PINCH1 |
Reference Data |
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