PP2A-alpha (PPP2CA) Rabbit Monoclonal Antibody [Clone ID: R06-8A4]

CAT#: TA385030

PP2A alpha/beta Rabbit monoclonal Antibody

Size: 20 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Clone Name R06-8A4
Applications IP, WB
Recommend Dilution WB: 1/1000-1/100
IP: 1/50
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Immunogen A synthetic peptide of human PP2A alpha
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size Calculated MW: 36 kDa; Observed MW: 36 kDa
Gene Name protein phosphatase 2 catalytic subunit alpha
Background Swiss-Prot Acc.P67775.PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I . Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
Synonyms PP2A-alpha; PP2Ac; PP2CA; PP2Calpha; RP-C
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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