Peroxiredoxin 1 (PRDX1) Mouse Monoclonal Antibody [Clone ID: 6A6-4H3-7A3]

Specifications

Product Data
Clone Name	6A6-4H3-7A3
Applications	IF, IHC, WB
Recommend Dilution	WB: 1/1000-3000 ICC: 1/100-200 IHC: 1/50-300
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Protein of Peroxiredoxin-1
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Observed MW (kDa):21
Gene Name	peroxiredoxin 1
Database Link	Entrez Gene 5052 Human UniProt ID Q06830
Background	Swiss-Prot Acc.Q06830.Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2 (PubMed:9497357). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation .
Synonyms	MSP23; NKEF-A; NKEFA; PAG; PAGA; PAGB; PRX1; PRXI; TDPX2
Reference Data

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