SCARB1 Rabbit Monoclonal Antibody [Clone ID: R07-4H3]

Specifications

Product Data
Clone Name	R07-4H3
Applications	IP, WB
Recommend Dilution	WB: 1/1000 IP: 1/20
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human Scavenging Receptor SR-BI
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 61 kDa; Observed MW: 80 kDa
Gene Name	scavenger receptor class B member 1
Database Link	Entrez Gene 949 Human UniProt ID Q8WTV0
Background	Swiss-Prot Acc.Q8WTV0.Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218).
Synonyms	CD36L1; CLA-1; CLA1; MGC138242; SR-BI; SRB1
Reference Data

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