SFRP4 Rabbit Monoclonal Antibody [Clone ID: R01-2C2]

Specifications

Product Data
Clone Name	R01-2C2
Applications	WB
Recommend Dilution	WB: 1/1000-1/5000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human SFRP4
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 40 kDa; Observed MW: 53-55 kDa
Gene Name	secreted frizzled related protein 4
Database Link	Entrez Gene 6424 Human UniProt ID Q6FHJ7
Background	Swiss-Prot Acc.Q6FHJ7.Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types . SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling . Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (PubMed:12952927).
Synonyms	FRP-4; FRPHE; MGC26498; sFRP-4
Reference Data

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