TRIM21 Mouse Monoclonal Antibody [Clone ID: 5B9-B9-H8]

Specifications

Product Data
Clone Name	5B9-B9-H8
Applications	WB
Recommend Dilution	WB: 1/1000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant human TRIM21 protein fragments expressed in E.coli.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	50kDa
Gene Name	tripartite motif containing 21
Database Link	Entrez Gene 6737 Human UniProt ID P19474
Background	Swiss-Prot Acc.P19474.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
Synonyms	RNF81; Ro(SS-A); RO52; SS-A; SSA; SSA1
Reference Data

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