TRIM25 Rabbit Monoclonal Antibody [Clone ID: R06-1H2]

CAT#: TA385464S

TRIM25 Rabbit monoclonal Antibody

Size: 20 ul 100 ul



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CNY 800.00


货期*
2周

规格
    • 20 ul

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Specifications

Product Data
Clone Name R06-1H2
Applications IF, IP, WB
Recommend Dilution WB: 1/1000-1/5000
ICC/IF: 1/50-1/200
IP: 1/20
Reactivity Human, Rat
Host Rabbit
Clonality Monoclonal
Immunogen A synthetic peptide of human TRIM25
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size Calculated MW: 71 kDa; Observed MW: 71 kDa
Gene Name tripartite motif containing 25
Background Swiss-Prot Acc.Q14258.Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784).
Synonyms EFP; RNF147; Z147; ZNF147
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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