CD4 Rabbit Monoclonal Antibody [Clone ID: MT310]

Specifications

Product Data
Clone Name	MT310
Applications	FC, IF, IHC, IP, WB
Reactivity	Human, Monkey
Host	Rabbit
Clonality	Monoclonal
Specificity	mt310 binds to the extracellular domain D1 of CD4 – the same site as the HIV-1 gp120-binding site mt310 can inhibit gp120 binding to CD4, which blocks HIV infectivity of CD4+ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation, possibly leading to the induction of anergy. Antibody binding to CD4 additionally causes the induction of GM-CSF, TNF-α (only after 20 h) and IL-10.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	CD4 molecule
Database Link	Entrez Gene 920 Human UniProt ID P01730
Synonyms	CD4mut
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.