CD28 Mouse Monoclonal Antibody [Clone ID: 1C6]
CNY 7,170.00
货期*
6周
规格
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | 1C6 |
Applications | Bl, ELISA, FC |
Reactivity | Dog |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Canine CD28. |
Specificity | The antibody binds specifically to canine CD28, a self self surface receptor expressed by thymocytes and a subset of natural killer cells. CD28 acts as a receptor for CD80 and CD86, providing a costimulatory signal for the activation of T-cells and the production of interleukins, such as IL-6. The 1C6 monoclonal antibody has antagonistic activity, blocking mixed lymphocyte reactions and cytotoxic T lymphocyte mediated killing. The use of the monoclonal antibody 1C6 for the neutralisation of CD26 signal following T-cell receptor activation is of clinical importance for transplantation therapy, as it has been shown to prevent graft rejection and graft-versus-host disease in the canine model of allogeneic hematopoietic cell transplantation (HCT). |
Formulation | PBS with 0.02% Proclin 300. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles. |
Database Link | |
Synonyms | MGC138290; Tp44 |
Reference Data |
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