Prion Mouse Monoclonal Antibody [Clone ID: 3F4]

Specifications

Product Data
Clone Name	3F4
Applications	ELISA, IHC, IP, WB
Reactivity	Hamster, Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Hamster 263K PrPs.
Specificity	The antibody binds specifically to prion, a misfolded protein that has the ability to enter healthy organisms and cause other misfolding of other proteins into their prion form. This plays an essential role in the pathogenesis of certain neurodegenerative disorders such as Creutzfeldt-Jakob disease (CJD), Gerstmann-Staussler syndrome (GSS) and bovine spongiform encephalopathy (BSE). These disorders are characterised by an accumulation of prion proteins in the brain, which have a disrupted secondary structure.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Note	This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.