MARCO Rabbit Monoclonal Antibody [Clone ID: PLK1]

Specifications

Product Data
Clone Name	PLK1
Applications	FC, IF, IHC, IP, WB
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	The antibody was raised by immunising BALB/c mice with human alveolar macrophages (AMs) and subsequent creation of hybridomas.
Specificity	This antibody recognises the extracellular domain V between residues 420 and 431 in MARCO both in human and bovine samples. The specificity of this antibody was confirmed in an IF experiment where the antibody stained alveolar macrophages for MACRO (Arredouani et al., 2005). Tissue samples prepared in acetone and paraformaldehyde were also successfully immunohistochemically stained (Arredouani et al., 2005; Martens et al., 2006). The antibody was also capable of weak staining of alveolar macrophages in flow cytometry (Palecanda and Kobzik, 2001). In IP experiments, the antibody immunoprecipitates MARCO from lysates obtained from COS cells transfected with human MARCO (Arredouani et al., 2005).
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	macrophage receptor with collagenous structure
Database Link	Entrez Gene 8685 Human UniProt ID Q9UEW3
Synonyms	SCARA2
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG3 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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