ERO1A Rabbit Polyclonal Antibody

CAT#: TA388207

ERO1A Rabbit polyclonal antibody



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Specifications

Product Data
Applications IHC, WB
Recommend Dilution Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant Human ERO1-like protein alpha protein (24-260AA)
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration lot specific
Purification Antigen Affinity Purified
Conjugation Unconjugated
Storage Condition Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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