VILIP1 (VSNL1) Mouse Monoclonal Antibody [Clone ID: 2D11]

Specifications

Product Data
Clone Name	2D11
Applications	ICC, IHC, WB
Recommend Dilution	WB: 1:2000 WB Brain: 1:2000 ICC: 1:500-1:1000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human VSNL1 purified from E. coli.
Specificity	Specific for endogenous levels of the ~22 kDa VSNL1 protein.
Formulation	PBS + 10 mM NaN3.
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Predicted Protein Size	22
Gene Name	visinin like 1
Database Link	Entrez Gene 7447 Human UniProt ID P62760
Background	Visinin-like protein 1 (VSNL1), also known as VILIP1, is a calcium sensor protein expressed exclusively in neurons. Highest levels of VSNL1 expression are found in cerebellar Purkinje cells. VSNL1 has been implicated in the modulation of cell signaling cascades via regulation of adenyl cyclase activity (Braunewell et al., 1997). Additionally, VSNL1 has been associated with amyloid plaques and neurofibrillar tangles in Alzheimer’s disease (Schnurra et al., 2001).
Synonyms	HLP3; HPCAL3; HUVISL1; OTTHUMP00000200482; OTTHUMP00000200483; VILIP; VILIP-1; VISL1; VLP-1
Note	Protein G purified culture supernatant.
Reference Data

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