Nfkbia Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:500 - 1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Formulation	PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	NFKB inhibitor alpha
Database Link	Entrez Gene 25493 Rat UniProt ID Q63746
Background	Enables NF-kappaB binding activity and heat shock protein binding activity. Involved in several processes, including cytoplasmic sequestering of NF-kappaB; leukocyte migration involved in inflammatory response; and liver regeneration. Acts upstream of or within cellular response to cytokine stimulus and cellular response to organic cyclic compound. Located in cytosol and nucleus. Part of protein-containing complex. Used to study gastritis; pulmonary emphysema; and sciatic neuropathy. Biomarker of several diseases, including acute necrotizing pancreatitis; alcoholic hepatitis; artery disease (multiple); middle cerebral artery infarction; and toxic shock syndrome. Human ortholog(s) of this gene implicated in several diseases, including childhood-onset asthma; hematologic cancer (multiple); hepatitis B; hepatitis C; and lung disease (multiple). Orthologous to human NFKBIA (NFKB inhibitor alpha).
Synonyms	I-kappa-B-alpha; IkappaBalpha; IkB-alpha; IKBA; MAD-3; MAD3; NFKBI
Reference Data

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